Technique to Regenerate Optic Nerve offers hope for future Glaucoma treatment

Eye

Scientists have used gene therapy to regenerate damaged nerve fibres in the eye, in a discovery that could aid the development of new treatments for glaucoma, one of the leading causes of blindness worldwide.

Axons — nerve fibres — in the adult central nervous system (CNS) do not normally regenerate after injury and disease, meaning that damage is often irreversible. However, over the past decade there have been a number of discoveries that suggest it may be possible to stimulate regeneration.

In a study published today in Nature Communications, scientists tested whether the gene responsible for the production of a protein known as Protrudin could stimulate the regeneration of nerve cells and protect them from cell death after an injury.

The team, led by Dr Richard Eva, Profe...

Read More

Blue Phosphorus: How a Semiconductor becomes a Metal

The international team modelled a two-layer buckled honeycomb structure of blue phosphorus by means of highly precise calculations on high-performance computers. The compound is very stable and due to the very small distance between the two layers, it has metallic properties.

Blue phosphorus, an atomically thin synthetic semiconductor, becomes metallic as soon as it is converted into a double layer. The scientists describe the possibility of constructing nanoscale, highly efficient transistors consisting of only one element.

The results of these investigations were published as highlight article in the current issue of the journal Physical Review Letters.

The chemical element phosphorus is considered one of the most essential elements for life...

Read More

Clay Subsoil at Earth’s Driest Place may signal Life on Mars

Atacama Desert landscape
Scientists from Cornell and Spain’s Centro de Astrobiología have found that Earth’s most arid desert – Chile’s Atacama Desert, shown above – may hold a key to finding microbial life on Mars.

Earth’s most arid desert may hold a key to finding life on Mars. Diverse microbes discovered in the clay-rich, shallow soil layers in Chile’s dry Atacama Desert suggest that similar deposits below the Martian surface may contain microorganisms, which could be easily found by future rover missions or landing craft.

Led by Cornell University and Spain’s Centro de Astrobiología, scientists now offer a planetary primer to identifying microbial markers on shallow rover digs in Martian clay, in their work published Nov. 5 in Nature Scientific Reports.

In that dry environment at Atacama,...

Read More

Why Protecting the Brain Against Infection Takes Guts

Confocal micrograph showing the superior saggital sinus in the mouse. Immune cells are shown in green lining this tube, and blood vessels in red
Confocal micrograph showing the superior saggital sinus in the mouse. Immune cells are shown in green lining this tube, and blood vessels in red
Credit: Zach Fitzpatrick

The brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed in human samples, has shown that the brain has a surprising ally in its protection: the gut.

The brain is arguably the most important organ in the body, as it controls most other body systems and enables reasoning, intelligence, and emotion. Humans have evolved a variety of protective measures to prevent physical damage to the brain: it sits in a solid, bony case — the skull — and is wrapped in three layers of watertight tissue known as the meninges.

What has...

Read More