Scientists from Nanyang Technological University, Singapore (NTU Singapore) and the Agency for Science, Technology and Research (A*STAR) have shown that applying ‘temporal pressure’ to the skin of mice can create a new way to deliver drugs.

In a paper published in Science Advances, the researchers showed that bringing together two magnets so that they pinch and apply pressure to a fold of skin, led to short term changes in the skin barrier and specifically the formation of “micropores” underneath its surface.

In tests, they showed t...

A research team, led by the U.S. Department of Energy’s (DOE) Argonne National Laboratory in collaboration with Northern Illinois University, has discovered a new electrocatalyst that converts carbon dioxide (CO2) and water into ethanol with very high energy efficiency, high selectivity for the desired final product and low cost. Ethanol is a particularly desirable commodity because it is an ingredient in nearly all U.S. gasoline and is widely used as an intermediate product in the chemical, pharmaceutical and cosmetics industries.

“The process resulting from our catalyst would contribute to the circular carbon economy, which entails the reu...

X-ray images give unprecedented view of extremely rare type of supernova. New information suggests that these supernovae start as compact stars that lose mass at the end of life. Calcium-rich supernovae are responsible for up to half the calcium in the entire universe. SN 2019ehk has the richest calcium emission of all known transients.

Called “calcium-rich supernovae,” these stellar explosions are so rare that astrophysicists h...

A drug candidate developed by Salk researchers, and previously shown to slow aging in brain cells, successfully reversed memory loss in a mouse model of inherited Alzheimer’s disease. The new research, published online in July 2020 in the journal Redox Biology, also revealed that the drug, CMS121, works by changing how brain cells metabolize fatty molecules known as lipids.

“This was a more rigorous test of how well this compound would work in a therapeutic setting than our previous studies on it,” says Pamela Maher, a senior staff scientist in the lab of Salk Professor David Schubert and the senior author of the new paper...