New Eye Drops may prevent a common cause of Blindness

QUASAR J1007+2115, OR PŌNIUĀʻENA
Credit: International Gemini Observatory/NOIRLab/NSF/AURA/P. Marenfeld


Researchers at Columbia University Irving Medical Center have developed eye drops that could prevent vision loss after retinal vein occlusion, a major cause of blindness for millions of adults worldwide.A study, in mice, suggests that the experimental therapy — which targets a common cause of neurodegeneration and vascular leakage in the eye — could have broader therapeutic effects than existing drugs.The study was published in Nature Communications.What is Retinal Vein Occlusion?Retinal vein occlusion occurs when a major vein that drains blood from the retina is blocked, usually due to a blood clot...

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Laser-Welded Sugar: Sweet way to 3D-print blood vessels

A sample of blood vessel templates that Rice University bioengineers 3D-printed using a special blend of powdered sugars. (Photo by B. Martin/Rice University)

Intricate sugar networks dissolve to create pathways for blood in lab-grown tissues. Bioengineers have shown they can keep densely packed cells alive in lab-grown tissues by creating complex networks of branching blood vessels from templates of 3D-printed sugar.

Powdered sugar is the special ingredient in a Rice University recipe for mimicking the body’s intricate, branching blood vessels in lab-grown tissues.

In research published in the journal Nature Biomedical Engineering, Rice bioengineers showed they could keep densely packed cells alive for two weeks in relatively large constructs.

“One of the biggest hurdles to e...

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Monster Black Hole found in the Early Universe

QUASAR J1007+2115, OR PŌNIUĀʻENA
Credit: International Gemini Observatory/NOIRLab/NSF/AURA/P. Marenfeld

The second-most distant quasar ever discovered now has a Hawaiian name. Astronomers have discovered the second-most distant quasar ever found using three Maunakea Observatories in Hawai’i: W. M. Keck Observatory, the international Gemini Observatory, a Program of NSF’s NOIRLab, and the University of Hawai’i-owned United Kingdom Infrared Telescope (UKIRT). It is the first quasar to receive an indigenous Hawaiian name, Poniua’ena, which means “unseen spinning source of creation, surrounded with brilliance” in the Hawaiian language.

Poniua’ena is only the second quasar yet detected at a distance calculated at a cosmological redshift greater than 7...

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Receptor makes Mice Strong and Slim

Mouse on exercise wheel | Credit: © Emilia Stasiak / stock.adobe.com

Molecule that regulates two side effects of aging identified. Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects. Experiments with human cell cultures suggest that the corresponding signaling pathways might also exist in humans. The study, which also involved researchers from Spain, Finland, Belgium, Denmark and the USA, has now been published in the journal Cell Metabolism.

The surfaces of some cells are virtually teeming with A2B receptors, for example in the so-called brown adipose tissue. Brown adipose tissue, unlike its white-colored counterpart, is not used to store fat. Instead, it burns fat and thereby generates heat.

“In our publication we to...

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