New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells—including cancer cells—regulate their genes.

The enzyme, LSD1, can “turn off gene expression by removing chemical flags (methyl groups) from the nucleosome—tightly packed units of DNA and protein in chromosomes. This LSD1 histone demethylase is over-expressed in multiple cancer types, resulting in disruption to normal cell development, and the new structure could inform therapeutic interventions that target the enzyme.

A paper by Penn State researchers describing the ...

Acoustic waves have been found to be highly versatile and promising carriers of information between chip-based electronic devices. This characteristic is ideal for the development of a number of electronic components, including microwave filters and transducers.

In the past, some researchers have tried to build devices in which waves are transmitted between two ports in a non-symmetric way. These are known as nonreciprocal devices. These devices could be particularly promising for the manipulation and routing of phonons, quasiparticles associated with acoustic waves...

Infrared dark clouds (IRDCs) are dark patches of cold dust and gas seen in the sky against the bright diffuse infrared glow of warm dust in our galaxy. These IRDCs, massive and rich in molecules, are natural sites for star birth—one of the main reasons why astronomers are actively studying them...

A dual-mechanism antibiotic kills Gram-negative bacteria and avoids drug resistance. Poison is lethal all on its own – as are arrows – but their combination is greater than the sum of their parts. A weapon that simultaneously attacks from within and without can take down even the strongest opponents, from E. coli to MRSA (methicillin resistant Staphylococcus aureus).

A team of Princeton researchers reported today in the journal Cell...