Computer Simulations Visualize how DNA converts Cells into Stem Cells

The pioneer transcription factor Oct4 (blue) binds to the nucleosome (a complex of proteins (green) and the DNA (orange) wrapped around these proteins). Credit: Jan Huertas and Vlad Cojocaru, ©MPI Münster, ©Hubrecht Institute.

Researchers of the Hubrecht Institute (KNAW — The Netherlands) and the Max Planck Institute in Münster (Germany) have revealed how an essential protein helps to activate genomic DNA during the conversion of regular adult human cells into stem cells. Their findings are published in the Biophysical Journal.

Signalling in the cell to start or stop reading DNA happens through proteins called transcription factors. Identity changes happen naturally during development as cells transition from an undesignated cell to a specific cell type...

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New Green Technology generates

The current Air-gen device can power small devices. Photos courtesy: UMass Amherst/Yao and Lovley labs.
The current Air-gen device can power small devices. Photos courtesy: UMass Amherst/Yao and Lovley labs.

Renewable device could help mitigate climate change, power medical devices. Scientists at the University of Massachusetts Amherst have developed a device that uses a natural protein to create electricity from moisture in the air, a new technology they say could have significant implications for the future of renewable energy, climate change and in the future of medicine.

As reported today in Nature, the laboratories of electrical engineer Jun Yao and microbiologist Derek Lovley at UMass Amherst have created a device they call an “Air-gen.” or air-powered generator, with electrically conductive protein nanowires produced by the microbe Geobacter...

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Hubble Embraces Spiral with Open Arms

spiral galaxy NGC 2008
The spiral galaxy NGC 2008 sits center stage, its ghostly spiral arms spreading out toward us, in this image captured by the NASA/ESA Hubble Space Telescope.

The spiral galaxy NGC 2008 sits center stage, its ghostly spiral arms spreading out toward us, in this image captured by the NASA/ESA Hubble Space Telescope.

This galaxy is located about 425 million light-years from Earth in the constellation of Pictor (the Painter’s Easel). Discovered in 1834 by astronomer John Herschel, NGC 2008 is categorized as a type Sc galaxy in the Hubble sequence, a system used to describe and classify the various morphologies of galaxies. The “S” indicates that NGC 2008 is a spiral, while the “c” means it has a relatively small central bulge and more open spiral arms...

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New Material has Highest Electron Mobility among known Layered Magnetic materials

Atoms in layered material
High mobility in a van der Waals layered antiferromagnetic metal. Science Advances, 2020; 6 (6): eaay6407 DOI: 10.1126/sciadv.aay6407

A new material has properties that make it a promising candidate for new areas like magnetic twistronic devices and spintronics, as well as advances in data storage and device design.

All the elements are there to begin with, so to speak; it’s just a matter of figuring out what they are capable of – alone or together. For Leslie Schoop’s lab, one recent such investigation has uncovered a layered compound with a trio of properties not previously known to exist in one material.

With an international interdisciplinary team, Schoop, assistant professor of chemistry, and Postdoctoral Research Associate Shiming Lei, published a paper last week in Scien...

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