A protein called Sestrin might be responsible for many of the benefits of a good workout. Michigan Medicine researchers studying a class of naturally occurring protein called Sestrin have found that it can mimic many of exercise’s effects in flies and mice. The findings could eventually help scientists combat muscle wasting due to aging and other causes.

“Researchers have previously observed that Sestrin accumulates in muscle following exercise,” said Myungjin Kim, Ph.D., a research assistant professor in the Department of Molecular & Integrative Physiology. Kim, working with professor Jun Hee Lee, Ph.D...

Michigan Medicine researchers studying a class of naturally occurring protein called Sestrin have found that it can mimic many of exercise’s effects in flies and mice. The findings could eventually help scientists combat muscle wasting due to aging and other causes.

“Researchers have previously observed that Sestrin accumulates in muscle following exercise,” said Myungjin Kim, Ph.D., a research assistant professor in the Department of Molecular & Integrative Physiology. Kim, working with professor Jun Hee Lee, Ph.D. and a team of researchers wanted to know more about the protein’s apparent link to exercise. Their first step was to encourage a bunch of flies to work out.

Taking advantage of Drosophila flies’ normal instinct to climb up and out of a test tube, their collaborators Robert Wess...

ESA’s XMM-Newton has discovered that gas lurking within the Milky Way’s halo reaches far hotter temperatures than previously thought and has a different chemical make-up than predicted, challenging our understanding of our galactic home.

A halo is a vast region of gas, stars and invisible dark matter surrounding a galaxy. It is a key component of a galaxy, connecting it to wider intergalactic space, and is thus thought to play an important role in galactic evolution.

Until now, a galaxy’s halo was thought to contain hot gas at a single temperature, with the exact temperature of this gas dependent on the mass of the galaxy.

However, a new study using ESA’s XMM-Newton X-ray space observatory now shows that the Milky Way’s halo contains no...

New light-sensitive material could eliminate some of the endoscopic procedures needed to remove gastrointestinal devices

A variety of medical devices can be inserted into the gastrointestinal tract to treat, diagnose, or monitor GI disorders. Many of these have to be removed by endoscopic surgery once their job is done. However, MIT engineers have now come up with a way to trigger such devices to break down inside the body when they are exposed to light from an ingestible LED.

The new approach is based on a light-sensitive hydrogel that the researchers designed...