B cells found to be crucial for long-term vaccine protection, new study shows

Photo of a man getting a vaccine

The new findings could help improve vaccine effectiveness in some immunocompromised patients. Researchers at the University of Colorado Anschutz Medical Campus have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 T cells, teaching them how to mount lasting defenses after vaccination.

The study was recently published in The Journal of Clinical Investigation.

“Think of CD8 T cells as rookie firefighters,” said lead author Jared Klarquist, PhD, assistant research professor of immunology and microbiology at the University of Colorado School of Medicine. “B cells teach the class on pacing. Without them, the rookies rush in, fight hard, and quit...

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Material? Robot? It’s a metabot

A researcher observes a metabot inside a magnetic chamber

In an experiment reminiscent of the Transformers movie franchise, engineers at Princeton University have created a type of material that can expand, assume new shapes, move and follow electromagnetic commands like a remotely controlled robot even though it lacks any motor or internal gears.

“You can transform between a material and a robot, and it is controllable with an external magnetic field,” said researcher Glaucio Paulino, the Margareta Engman Augustine Professor of Engineering at Princeton.

In an article published April 23 in the journal Nature, the researchers describe how they drew inspiration from the folding art of origami to create a structure that blurs the lines between robotics and materials...

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Innovative approaches advance search for ice on the moon

An artist rendering of what a future cosmic ray radar instrument could look like, attached to a satellite orbiting the Moon. Credit: Christian Miki, Department of Physics, UH Manoa.

Scientists and space explorers have been on the hunt to determine where and how much ice is present on the Moon. Water ice would be an important resource at a future lunar base, as it could be used to support humans or be broken down to hydrogen and oxygen, key components of rocket fuel. University of Hawai’i at Manoa researchers are using two innovative approaches to advance the search for ice on the Moon.

ShadowCam scouts for surface ice

Water ice was previously detected in the permanently shaded regions of the Moon’s north and south poles by Shuai Li, assistant researcher at the Hawai’i Institute o...

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Multiple studies show that children face elevated health risks after COVID infection

child in mask
Credit: Pixabay/CC0 Public Domain

Long COVID can result in increased risk for a variety of serious health problems for young people, including those affecting the kidney, gut, and cardiovascular system, according to a group of new studies led by investigators at the Perelman School of Medicine at the University of Pennsylvania.

“While most public attention has focused on the acute phase of COVID-19, our findings reveal children face significant long-term health risks that clinicians need to monitor,” said senior author Yong Chen, Ph.D., a professor in the Department of Biostatistics and Epidemiology. The studies were conducted under the Researching COVID to Enhance Recovery (RECOVER) Initiative, a special project including more than two dozen health care institutions.

These medic...

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