GIST Research reveals a promising new target to thwart Alzheimer’s decades before symptoms start

A person will have Alzheimer’s years before ever knowing it. The disorienting erasure of memories, language, thoughts—in essence, all that makes up one’s unique sense of self—is the final act of this enigmatic disease that spends decades disrupting vital processes and dismantling the brain’s delicate structure.

Once symptoms surface and doctors make a diagnosis, though, it can often be too late. Damage is widespread, impossible to reverse. No cure exists.

Attempts to develop drugs that clear away toxic accumulations of amyloid-beta and tau proteins—hallmarks of the disease that cause neurons to die—have ended in hundreds of failed clinical trials. Today, some scientists are skeptical over whether removing amyloid plaques is even enough...

Read More

Hit the wrong spot and an asteroid returns on a collision course

Asteroid deflection could save Earth, or accidentally doom it, depending on where we aim the impact.

Scientists caution that asteroid deflection must be precise, as striking the wrong spot risks sending it through a gravitational keyhole that sets up a future collision with Earth. Using lessons from NASA’s DART mission, researchers are developing probability maps to guide safer impact strategies.

Selecting the right spot to smash a spacecraft into the surface of a hazardous asteroid to deflect it must be done with great care, according to new research presented at the EPSC-DPS2025 Joint Meeting this week in Helsinki...

Read More

Rapamycin linked to DNA damage resilience in aging human immune cells

DNA
DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH

University of Oxford-led research finds low-dose rapamycin functions as a genomic protector in aging human immune cells, lowering DNA damage.

The mechanistic target of rapamycin (mTOR) is a central signaling pathway that regulates and coordinates cell growth, metabolism, and survival in response to environmental cues. It helps cells integrate signals from growth factors, nutrients, and stress to control whether they are in an anabolic (building up) or catabolic (breaking down) state.

Aging immune systems accumulate DNA damage linked to immunosenescence. Rapamycin is a drug that inhibits the mTOR pathway...

Read More

Light-based chip can boost power efficiency of AI tasks up to 100-fold

New light-based chip boosts power efficiency of AI tasks 100 fold
A newly developed silicon photonic chip turns light-encoded data into instant convolution results. Credit: H. Yang (University of Florida)

A team at the University of Florida has developed a new kind of computer chip that uses light with electricity to perform one of the most power-intensive parts of artificial intelligence—image recognition and similar pattern-finding tasks. Using light dramatically cuts the power needed to perform these tasks, with efficiency 10 or even 100 times that of current chips performing the same calculations. Using this approach could help rein in the enormous demand for electricity that is straining power grids while enabling higher performance AI models and systems.

Artificial intelligence (AI) systems are increasingly central to technology, powering ...

Read More