Breakthrough Research Makes Cancer-fighting Viral Agent More Effective

Cancer cells.
Credit: iStock.

Researchers from Aarhus University have made a significant breakthrough by discovering that the drug 4-OI can enhance the effectiveness of a cancer-fighting viral agent. This may lead to treatment of cancers that are otherwise resistant to therapies.

When a cancer cell doesn’t respond to traditional therapies, doctors may turn to a sort of viral biological warfare, by deploying ‘troops’ in the form of viral agents that are specifically engineered to target and eliminate cancer cells. The mode of attack is to transform the tumor into an immunologically “hot” environment, making it more visible and recognisable to our immune system.

Now, researchers from the Department of Biomedicine at Aarhus University have found a way to make one strain of viral agents even more ...

Read More

Wireless Receiver Blocks Interference for Better Mobile Device Performance

A cellphone has a blue shield which blocks red interference.
Caption: A new receiver can block up to four times more interference than some similar devices.
Credits:Image: MIT News; iStock

The growing prevalence of high-speed wireless communication devices, from 5G mobile phones to sensors for autonomous vehicles, is leading to increasingly crowded airwaves. This makes the ability to block interfering signals that can hamper device performance an even more important — and more challenging — problem.

With these and other emerging applications in mind, MIT researchers demonstrated a new millimeter-wave multiple-input-multiple-output (MIMO) wireless receiver architecture that can handle stronger spatial interference than previous designs. MIMO systems have multiple antennas, enabling them to transmit and receive signals from different directions...

Read More

Scientists Clarify Origins of Lunar Metallic Iron

Scientists clarify origins of lunar metallic iron
Characterizations of ULnpFe0 on extremities of impact glass beads. Credit: Institute of Physics

“We discovered that the glass beads in the Chang’e-5 lunar soil can preserve iron particles of different sizes, from about 1 nanometer to 1 micrometer,” said Prof. Bai.

“It is generally difficult to distinguish npFe0 of different origins observed together in single samples. Here we used the rotation feature of the impact glass beads to clearly distinguish npFe0 formed before and after the solidification of the host glass beads.”

In this study, the scientists found numerous discrete large npFe0, tens of nanometers in size, which tended to concentrate towards the extremities of the glass beads. This concentration effect can cause ultralarge npFe0 to protrude from the extremities.

Suc...

Read More

Serotonin 2C Receptor Regulates Memory in Mice and Humans: Implications for Alzheimer’s Disease

Artists rendition of a brain and neuron activity in a gold color.

Researchers at Baylor College of Medicine, the University of Cambridge in the U.K. and collaborating institutions have shown that serotonin 2C receptor in the brain regulates memory in people and animal models. The findings, published in the journal Science Advances, not only provide new insights into the factors involved in healthy memory but also in conditions associated with memory loss, like Alzheimer’s disease, and suggest novel avenues for treatment.

“Serotonin, a compound produced by neurons in the midbrain, acts as a neurotransmitter, passing messages between brain cells,” said co-corresponding author Dr. Yong Xu, professor of pediatrics—nutrition and associate director for basic sciences at the USDA/ARS Children’s Nutrition Research Center at Baylor.

“Serotonin-produc...

Read More