S. PEPITEM – a Novel Protective Agent for ‘Inflammageing’

Senior woman hand pain

A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against ‘inflammageing’, which is widely believed to be the root cause of many age-related diseases.

The study, published today in the journal npj Aging, raises the exciting possibility of a protective agent that could dampen age-related inflammation and restore normal immune function in older adults.

PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration) was initially identified at the University of Birmingham in 2015. While the role of the PEPITEM pathway has already been demonstrated in immune-mediated diseases, this is the first data showing that PEPITEM has the potential to increase healthspan in an aging population.

Researchers, led by Drs M...

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Novel Electrode for Improving Flowless Zinc-Bromine Battery

Image title: Nitrogen-Doped Mesoporous Carbon-Coated Graphite Felt Electrodes
Image caption: The novel electrodes effectively suppress the crossover of bromine and bromine complexe
s, thus preventing self-discharge and enhancing the electrochemical performance and cycling stability of flowless zinc-bromine batteries.
Image credit: Chanho Pak from Gwangju Institute of Science and Technology
License type: Original Content
Usage restrictions: Cannot be reused without permission

Researchers developed a novel electrode that effectively suppresses the harmful self-discharge phenomenon in flowless zinc-bromine batteries. The flowless zinc-bromine battery (FLZBB) is a promising alternative to flammable lithium-ion batteries due to its use of non-flammable electrolytes...

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Exoplanet-Hunting Telescope to begin Search for Another Earth in 2026

An artist's impression of the European Space Agency's PLATO spacecraft.
An artist’s impression of the European Space Agency’s PLATO spacecraft.
Credit
ESA/ATG medialab
Licence type Attribution (CC BY 4.0)

Europe’s next big space mission – a telescope that will hunt for Earth-like rocky planets outside of our solar system — is on course to launch at the end of 2026.

PLATO, or PLAnetary Transits and Oscillations of stars, is being built to find nearby potentially habitable worlds around Sun-like stars that we can examine in detail.

The space telescope will blast into orbit on Europe’s new rocket, Ariane-6, which made its maiden flight last week after being developed at a cost of €4billion (£3.4billion).

Dr David Brown, of the University of Warwick, is giving an update on the mission at the Royal Astronomical Society’s National Astronomy Meeting at t...

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Study identifies RNA molecule that Regulates Cellular Aging

SNORA13 (red) in the nucleus of senescent human cells
This shows SNORA13 (red) in the nucleus of senescent human cells within a specialized structure called the nucleolus where ribosomes are assembled. DNA is stained in blue.

A team led by UT Southwestern Medical Center researchers has discovered a new way that cells regulate senescence, an irreversible end to cell division. The findings, published in Cell, could one day lead to new interventions for a variety of conditions associated with aging, including neurodegenerative and cardiovascular diseases, diabetes, and cancer, as well as new therapies for a collection of diseases known as ribosomopathies.

“There is great interest in reducing senescence to slow or reverse aging or aging-associated diseases...

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