The familiar labels “night owl” and “early bird,” long used in sleep research, don’t fully capture the diversity of human internal clocks, a new study has found. The McGill University-led study published in Nature Communications found the two sleep-wake patterns, called chronotypes, contain a total of five distinct biological subtypes, each associated with different patterns of behavior and health.

A chronotype is based on the parts of a 24-hour period when a person naturally feels most alert or ready to sleep. Previous research has linked late chronotypes to worse health outcomes, but results have often been inconsistent. The new findings help explain why, the authors said.

“Rather than asking whether night owls are more at risk, the better question may be...

Additive manufacturing has revolutionized manufacturing by enabling customized, cost-effective products with minimal waste. However, with the majority of 3D printers operating on open-loop systems, they are notoriously prone to failure...

A Sydney Ph.D. student has recreated a tiny piece of the universe inside a bottle in her laboratory, producing cosmic dust from scratch. The results shed new light on how the chemical building blocks of life may have formed long before Earth existed. Linda Losurdo, a Ph.D. candidate in materials and plasma physics in the School of Physics, used a simple mix of gases—nitrogen, carbon dioxide and acetylene—to mimic the harsh and dynamic environments around stars and supernova remnants.

By subjecting these gases to intense electrical energy, she generated carbon-rich “cosmic dust” similar to the material found drifting between stars and embedded in comets, asteroids and meteor...

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body’s response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from berries, tea, and other plant-based foods. The research reveals that this molecule acts as an immune-system amplifier, boosting the body’s inflammatory defenses during early infection but elevating them to deadly levels when infections progress to sepsis.

Published in Cell Reports, the study demonstrates that elevated hippuric acid levels correlate with increased mortality in sepsis patients, while also uncovering the molecular mechanisms by which this metabolite modifies immune re...