Study: In patients with Long COVID, Immune cells don’t follow the rules

Kailin Yin speaking with Nadia Roan in the lab
Kailin Yin (left), a postdoctoral fellow in the Roan Lab and co-first author of the study, collaborates with Gladstone Senior Investigator Nadia Roan. Their study revealed unusual activity among certain immune cells in people with long COVID.

People with long COVID have dysfunctional immune cells that show signs of chronic inflammation and faulty movement into organs, among other unusual activity, according to a new study by scientists at Gladstone Institutes and UC San Francisco (UCSF).

The team analyzed immune cells and hundreds of different immune molecules in the blood of 43 people with and without long COVID...

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Novel AI Framework Generates Images from nothing

A new, potentially revolutionary artificial intelligence framework called “Blackout Diffusion” generates images from a completely empty picture, meaning that, unlike other generative diffusion models, the machine-learning algorithm does not require initiating a “random seed” to get started.

Blackout Diffusion, presented at the recent International Conference on Machine Learning, generates samples that are comparable to the current diffusion models, such as DALL-E or Midjourney but require fewer computational resources than these models.

“Generative modeling is bringing in the next industrial revolution with its capability to assist many tasks, such as generation of software code, legal documents, and even art,” said Javier Santos, an AI researcher at Los Alamos National Laboratory a...

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Fermi Gamma-ray Space Telescope detects Surprise Gamma-Ray feature Beyond our Galaxy

Artist's concept of gamma ray sky with dipole marked in magenta
This artist’s concept shows the entire sky in gamma rays with magenta circles illustrating the uncertainty in the direction from which more high-energy gamma rays than average seem to be arriving. In this view, the plane of our galaxy runs across the middle of the map. The circles enclose regions with a 68% (inner) and a 95% chance of containing the origin of these gamma rays.
NASA’s Goddard Space Flight Center

Astronomers analyzing 13 years of data from NASA’s Fermi Gamma-ray Space Telescope have found an unexpected and as yet unexplained feature outside of our galaxy.

“It is a completely serendipitous discovery,” said Alexander Kashlinsky, a cosmologist at the University of Maryland and NASA’s Goddard Space Flight Center in Greenbelt, who presented the research at the 243rd mee...

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Scientists Identify how Dietary Restriction Slows Brain Aging and Increases Lifespan

Scientists identify how dietary restriction slows brain aging and increases lifespan
mtd interacts with the retromer complex and is required for retromer maintenance. Credit: Nature Communications (2024). DOI: 10.1038/s41467-023-44343-3

Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Buck Institute for Research on Aging scientists have uncovered a role for a gene called OXR1 that is necessary for the lifespan extension seen with dietary restriction and is essential for healthy brain aging.

“When people restrict the amount of food that they eat, they typically think it might affect their digestive tract or fat buildup, but not necessarily about how it affects the brain,” said Kenneth Wilson, Ph.D...

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