Sinai Health study identifies new concepts for GLP-1 action in the brain, the 2023 Science magazine breakthrough of the year

A woman stands facing the camera smiling. She is in a therapy gym in a hospital and there are  dumbells and other equipment in the background

Researcher Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named the 2023 breakthrough of the year by the Science Magazine. Not only have millions of people with type 2 diabetes benefitted from GLP-1 agonists, but the drugs also produced wide-ranging health benefits beyond weight loss in two recent patient trials.

For years, GLP-1 agonists have been known to have a fortuitous side effect of improving metabolic health, but how this is regulated in the body remains unclear. Now Dr. Drucker, who has dedicated his life’s work to understanding how these drugs work, has a new paper that begins to unravel the mystery with a novel finding—it all starts in the brain.

His team at the Lunenfeld-Tanenbaum Research Institute...

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Ultrafast Lasers Map Electrons ‘going ballistic’ in Graphene with implications for Next-gen Electronic devices

Ultrafast lasers map electrons 'going ballistic' in graphene, with implications for next-gen electronic devices

Research appearing in ACS Nano reveals the ballistic movement of electrons in graphene in real-time.

The observations made at the University of Kansas’ Ultrafast Laser Lab could lead to breakthroughs in governing electrons in semiconductors, fundamental components in most information and energy technology.

“Generally, electron movement is interrupted by collisions with other particles in solids,” said lead author Ryan Scott, a doctoral student in KU’s Department of Physics & Astronomy.

“This is similar to someone running in a ballroom full of dancers. These collisions are rather frequent—about 10 to 100 billion times per second. They slow down the electrons, cause energy loss, and generate unwanted heat...

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Second Radio Relic discovered in the Galaxy Cluster Abell 2108

Second radio relic discovered in the galaxy cluster Abell 2108
Color composite image of Abell 2108 showing Pan-STARRS ‘r’ band optical image in green, XMM-Newton X-ray in blue, and uGMRT point source removed radio image in red. Credit: arXiv (2023). DOI: 10.48550/arxiv.2312.04170

Astronomers from India and Taiwan have used the upgraded Giant Metrewave Radio Telescope (uGMRT) to perform radio observations of a galaxy cluster known as Abell 2108. As a result, they detected a second radio relic, which is much larger and differs in morphology from the previously identified relic in this cluster. The finding was reported in a paper published Dec. 7 on the pre-print server arXiv.

Radio relics are diffuse, elongated radio sources of synchrotron origin...

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Webb Rings in Holidays with Ringed Planet Uranus

The planet Uranus on a black background. The planet appears blue with a large, white patch taking up the right half. The patch is whitest at the center, then fades into blue at it expands from right to left. A thin outline of Uranus is also white. Around the planet is a system of nested rings. The outermost ring is the brightest while the innermost ring is the faintest. Unlike Saturn’s horizontal rings, the rings of Uranus are vertical and so they appear to surround the planet in an oval shape. There are 9 blueish white dots scattered around the rings.
This image of Uranus from NIRCam (Near-Infrared Camera) on NASA’s James Webb Space Telescope exquisitely captures Uranus’s seasonal north polar cap and dim inner and outer rings. This Webb image also shows 9 of the planet’s 27 moons – clockwise starting at 2 o’clock, they are: Rosalind, Puck, Belinda, Desdemona, Cressida, Bianca, Portia, Juliet, and Perdita.
NASA, ESA, CSA, STScI

The James Webb Space Telescope recently trained its sights on unusual and enigmatic Uranus, an ice giant that spins on its side. Webb captured this dynamic world with rings, moons, storms, and other atmospheric features—including a seasonal polar cap. The image expands upon a two-color version released earlier this year, adding additional wavelength coverage for a more detailed look.

With its exq...

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