Experimental Therapy Eases Alzheimer’s Signs, Symptoms in Mice

Experimental therapy eases alzheimer's signs, symptoms in mice
A new cellular therapy improved learning and memory in mice with Alzheimer’s disease, researchers report.

The therapy—developed at the University of Nebraska Medical Center (UNMC)—relies on both the immune system to fight key aspects of Alzheimer’s, plus modified cells that zero in on the brain protein plaques that are a hallmark of the disease.

In patients with Alzheimer’s, amyloid-beta protein forms plaques that prevent nerve cells from signaling each other. One theory is that this might cause irreversible memory loss and behavior changes characteristic of Alzheimer’s disease.

The new study was recently published in the journal Molecular Neurodegeneration. Researchers used genetically modified immune-controlling cells called Tregs to target amyloid-beta.

When the UNMC te...

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A New Way to Characterize Habitable Planets

For decades, science fiction authors have imagined scenarios in which life thrives on the harsh surfaces of Mars or our moon, or in the oceans below the icy surfaces of Saturn’s moon Enceladus and Jupiter’s moon Europa. But the study of habitability—the conditions required to support and sustain life—is not just confined to the pages of fiction. As more planetary bodies in our solar system and beyond are investigated for their potential to host conditions favorable to life, researchers are debating how to characterize habitability.

While many studies have focused on the information obtained by orbiting spacecraft or telescopes that provide snapshot views of ocean worlds and exoplanets, a new paper emphasizes the importance of investigating complex geophysical factors that can b...

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Fascia: The most Neglected Part of our Body is Finally Starting to Receive Attention

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We are constantly reminded about how exercise benefits our bone and muscle health or reduces fat. However, there is also a growing interest in one element of our anatomy that is often overlooked: our fascia.

Fascia is a thin casing of connective tissue, mainly made of collagen—a rope-like structure that provides strength and protection to many areas of the body. It surrounds and holds every organ, blood vessel, bone, nerve fiber and muscle in place. And scientists increasingly recognize its importance in muscle and bone health.

It is hard to see fascia in the body, but you can get a sense of what it looks like if you look at a steak. It is the thin white streaks on the surface or between layers of the meat.

Fascia provides general and special f...

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Apple Flash: Our Smart Devices will Soon be Smarter

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Credit: Pixabay/CC0 Public Domain

Our smart devices take voice commands from us, check our heartbeats, track our sleep, translate text, send us reminders, capture photos and movies, and let us talk to family and friends continents away.

Now imagine turbocharging those capabilities. Holding in-depth, natural language exchanges on academic or personal queries; running our vital signs through a global database to check on imminent health issues; packing massive databases to provide comprehensive real-time translation among two or more parties speaking different languages; and conversing with GPS software providing details on the best burgers, movies, hotels or people-watching spots trending along your route.

Tapping into the seductive power of large language models and natural langu...

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