A New Mechanism Encouraging the Brain to Self-Repair After an Ischemic Stroke

Lipid metabolism triggering brain-autonomous neural repair after ischemic stroke
The neurons around an injured brain region will play major roles in promoting functional recovery through nervous system development, synapse organization, and remyelination; however, the molecular mechanisms triggering such a broad range of neural repair after brain injury remained unknown. Our study demonstrated that the secretion of PLA2G2E from perilesional neurons with ischemic stress generated DGLA and 15-HETrE, which triggered these recovery processes through the neuronal Padi4-dependent induction of cluster formation associated with neural repair after ischemic brain injury.

Partial recovery after ischemic stroke is possible, but the mechanisms involved in this process remain unclear...

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Tubular Tissue Advance could pave way for Lab-grown Blood Vessels

Human cells in red, green or blue are arranged in layers to create a microscopic cell rainbow against a black background

Innovative technology that creates ultra-thin layers of human cells in tube-like structures could spur development of lifelike blood vessels and intestines in the lab.

The technique, known as RIFLE – rotational internal flow layer engineering – enables the construction of separate layers as delicate as one cell thick.

Such versatility is crucial to developing accurate human models of layered tubular tissue for use in research, offering an important alternative to animal models, experts say.

Scientists have been able to demonstrate the technology by manufacturing cells into super-thin layers that mirror those seen in a human blood vessel.

Layered tubular tissue is found throughout the body — in blood vessels, the digestive tract and other organs...

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Physicists Demonstrate how Sound can be Transmitted through Vacuum

Sound waves tunneling across a vacuum gap

A classic movie was once promoted with the punchline: “In space, no one can hear you scream.” Physicists Zhuoran Geng and Ilari Maasilta from the Nanoscience Center at the University of Jyväskylä, Finland, have demonstrated, on the contrary, that in certain situations sound can be transmitted strongly across a vacuum region!

In a recent publication they show that in some cases a sound wave can jump or “tunnel” fully across a vacuum gap between two solids if the materials in question are piezoelectric. In such materials, vibrations (sound waves) produce an electrical response, as well, and since an electric field can exist in vacuum, it can transmit the sound waves across...

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Astronomers Discover a Forming Quadruple-Star System

G206.93-16.61E2 is close to the reflection nebula NGC 2023 in the Orion B molecular cloud. The Zoom-in pictures show the 1.3mm continuum emission (blue) and CO molecular outflow (orange) of ALMA observation. These observations develop an in-depth understanding of the formation of multiple star systems in the early stage.
 (Image by SHAO)
 

Recently, the international team ALMA Survey of Orion Planck Galactic Cold Clumps (ALMASOP) led by Prof. Liu Tie from Shanghai Astronomical Observatory (SHAO) of the Chinese Academy of Sciences conducted a high-resolution investigation on 72 dense cores in the Orion Giant Molecular Clouds (GMCs) with the Atacama Large Millimeter/submillimeter Array (ALMA), and discovered a forming quadruple-star system within one core...

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