Researchers Find that Targeting Immune Cells May Help Treat Atrial Fibrillation

New study finds that macrophages and macrophage-produced proteins contribute to heartbeat irregularities. Targeting these cells may therefore represent a promising strategy to treat and prevent AFib.

Current treatments for atrial fibrillation (AFib), a common heart condition characterized by fast and irregular beats that can lead to stroke and heart failure, have multiple side effects and are ineffective for preventing AFib recurrence.

New research led by investigators at Massachusetts General Hospital (MGH) and published in Science reveals that certain immune cells play a major role in the development of AFib. Targeting these cells may therefore represent a promising strategy to treat and prevent AFib.

For the work, senior author Matthias Nahrendorf, MD, PhD, an investigator...

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Nanomedicine for Treating Inflammatory Bowel Disease

Schematic summary of the overall flow of the study, showing GlyNPs(BR) library synthesis and characterizations of the constructed GlyNP(BR) library.
Schematic summary of the overall flow of the study, showing GlyNPs(BR) library synthesis and characterizations of the constructed GlyNP(BR) library. 

Anti-inflammatory nanoparticles mimic glycocalyx. Chronic inflammatory bowel disease (IBD), such as Crohn’s disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects. In the journal Angewandte Chemie, a South Korean research team has now introduced a new method of treatment. It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine.

Stomach cramps and severe diarrhea, often accompanied by significant weight loss, are some o...

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Giant Swirling Waves at Edge of Jupiter’s Magnetosphere

Graph of KHI at Jupiter showing swirling waves
UCAR/Zhang, et.al. An SwRI-led team identified intermittent evidence of Kelvin-Helmholtz instabilities, giant swirling waves, at the boundary between Jupiter’s magnetosphere and the solar wind that fills interplanetary space, modeled here by University Corporation for Atmospheric Research scientists in a 2017 GRL paper.

Waves produced by Kelvin-Helmholtz instabilities transfer energy in the solar system. A team led by Southwest Research Institute (SwRI) and The University of Texas at San Antonio (UTSA) has found that NASA’s Juno spacecraft orbiting Jupiter frequently encounters giant swirling waves at the boundary between the solar wind and Jupiter’s magnetosphere...

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Researchers introduce Transparent Optical Imager with Near-Infrared Sensitivity and Touchless Interface

A transparent optical imager with near-infrared sensitivity and a touchless interface
a, Schematic of a large-area, 16 × 16 visually transparent NIR-sensitive OPD array (imager) that is placed in front of a laptop display. b, Schematic of the touchless user interface demo using NIR-emitting penlight. c, Photograph of the touchless user interface demo using NIR-emitting penlight. d, Schematic of a large-area, 16 × 16 visually transparent NIR-sensitive OPD array (imager) with integrated NIR LEDs that is placed in front of a laptop display. e, Schematic of the touchless user interface demo using gesture recognition of reflected NIR light. f, Photograph of the touchless user interface demo using gesture recognition of reflected NIR light. Credit: Nature Electronics (2023). DOI: 10.1038/s41928-023-00970-8

Most existing devices are operated via the sense of touch,...

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