Scientists deliver siRNA Therapy to Lung

Fluoresce images of lung tissue after treatment (top, red), show local distribution of chemically modified siRNA and robust gene silencing in the lung.

Delivery technology successfully blocks SARS-CoV-2 infection in mice; adaptable for multiple diseases

Scientists at UMass Chan Medical School have developed a technology to deliver gene therapy directly to lung tissue through intranasal administration, a development that could potentially create a new class of treatments for lung disease.

Published in the journal Proceedings of the National Academy of Sciences, the study by a multidisciplinary team of RNA biologists, chemical biologists, immunologists and virologists describes the delivery of siRNA molecules locally to lung tissue...

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Wearable Ultrasound Patch provide Non-Invasive Deep Tissue Monitoring

Optical images of the devices when twisted and stretched, showing its mechanical compliance and robustness, and conforming to the lateral shoulder joint and neck for tissue stiffness monitoring. Jacobs School of Engineering, University of California San Diego.
Optical images of the devices when twisted and stretched, showing its mechanical compliance and robustness, and conforming to the lateral shoulder joint and neck for tissue stiffness monitoring. Jacobs School of Engineering, University of California San Diego.

More effectively measuring tissue stiffness could help treat cancer, sports injuries and more. A team of engineers at the University of California San Diego has developed a stretchable ultrasonic array capable of serial, non-invasive, 3D imaging of tissues as deep as four centimeters below the surface of human skin, at a spatial resolution of 0.5 millimeters. This new method provides a non-invasive, longer-term alternative to current methods, with improved penetration depth.

The research emerges from the lab of Sheng Xu, a pro...

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A Stormy, Active Sun may have Kickstarted Life on Earth

An animation of the sun shows a bright spot, from which erupts a cloud of solar material and burst of bright particles.
A close up of a solar eruption, including a solar flare, a coronal mass ejection, and a solar energetic particle event.
Credits: NASA’s Goddard Space Flight Center

The first building blocks of life on Earth may have formed thanks to eruptions from our sun, a new study finds.

A series of chemical experiments show how solar particles, colliding with gases in Earth’s early atmosphere, can form amino acids and carboxylic acids, the basic building blocks of proteins and organic life. The findings were published in the journal Life.

To understand the origins of life, many scientists try to explain how amino acids, the raw materials from which proteins and all cellular life, were formed...

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‘Raw’ data show AI Signals Mirror how the Brain Listens and Learns

University of California, Berkeley, researchers have measured brain waves in participants and artificial intelligence systems — a comparison they say provides a window into what is considered a black box of AI. (Photo courtesy iStock)

University of California, Berkeley, researchers have measured brain waves in participants and artificial intelligence systems – a comparison they say provides a window into what is considered a black box of AI.

New research from the University of California, Berkeley, shows that artificial intelligence (AI) systems can process signals in a way that is remarkably similar to how the brain interprets speech, a finding scientists say might help explain the black box of how AI systems operate.

Using a system of electrodes placed on participants’ heads,...

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