Sugar-free diets may disrupt the gut microbiome, animal study indicates

Eliminating sugar from your diet may be more detrimental than previously thought, according to an animal study presented at ENDO 2026, the Endocrine Society’s annual meeting in Chicago.

“Completely removing sucrose from a low-fat diet may unexpectedly disrupt gut health and promote inflammation and metabolic dysfunction, highlighting that balanced nutrition is more important than simply eliminating sugar,” said Rasheed Ahmad, Ph.D., principal scientist and head of the Immunology & Microbiology Department at the Dasman Diabetes Institute in Kuwait City, Kuwait. The institute was founded by Kuwait Foundation for the Advancement of Sciences.

Researchers investigated the effects of a sucrose-free low-fat diet compared with a sucrose-containing low-fat control diet in two groups of m...

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Copper thin films reveal ballistic electron transport that could reshape future chip wiring

Ballistic transport demonstrated in thin films of copper, an industry-standard metal
a, Scanning electron microscopy (SEM) image of a Hall bar device with a channel width (W) of 150 nm. b, Cross-sectional transmission electron microscopy (TEM) image of the Hall bar device. c, Schematic illustration of the bend resistance measurement. d, Temperature dependence of the bend resistance measured in Hall bar devices with channel widths of 10 μm, 1 μm, 250 nm, and 150 nm. Credit: POSTECH

A joint research team has experimentally observed ballistic transport in single-crystalline copper thin films, demonstrating that ballistic transport is achievable in an industry-standard metal at interconnect-relevant dimensions. The study, titled “Ballistic transport in nanodevices based on single-crystalline Cu thin films,” was published in Nature Communications.

Ballistic transport r...

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Astrochemical model digs into the universe’s missing sulfur

Representation of how VUV photons break up sulfur molecules. Credit - Olli Sipilä
Representation of how VUV photons break up sulfur molecules. Credit – Olli Sipilä

Sulfur is one of the most abundant elements in the universe. If you peer into a diffuse interstellar cloud, you find loads of it—about the amount expected based on fusion patterns in the stars it was born in. However, if you look at a dense, cold molecular cloud—the kind where those stars actually form—it seems like 99% of the sulfur expected to be there is missing. Scientists have puzzled over this “missing sulfur problem” for decades, though a leading theory is that the element hides in icy dust grains, making it hard to detect.

A new paper published in Astronomy & Astrophysics from the Max Planck Institute for Extraterrestrial Physics and the Centro de Astrobiologia describes a new computer s...

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Faulty protein cleanup gene tied to severe early-onset neurological disorders

Evidence builds for the role malfunctioning protein removal systems play in neurodegenerative diseases
Left: Nerve fibers from healthy brain tissue are shown in magenta with support cells called glia in green. Right: Neurons deprived of PI31 are swollen and damaged. Glia are activated and enlarged as they try to remove faulty connections between cells. Credit: Steller lab

Though protein clumps associated with Alzheimer’s and Parkinson’s were discovered more than a century ago, researchers remain largely unable to prevent them from forming or eliminate them from the brain. And though a variety of therapies have taken aim at tau tangles, beta-amyloid plaques and Lewy bodies, among other notorious aggregates, none have been very effective at stopping disease progression.

Rockefeller’s Hermann Steller and his team in the Strang Laboratory of Apoptosis and Cancer Biology have long been fo...

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