Previously Unknown Cell Mechanism could help Counter Cancer and Aging

•Histone H2A-H2B are recycled during DNA replication independent of H3-H4
•H2A.Z and H2BK120ub1 mark nascent chromatin prior to transcription re-start
•H2A-H2B modification and variant landscapes are restored rapidly after replication
•H2AK119ub1 facilitates accurate and timely restoration of H3K27me3 post-replication

In a new study, researchers discovered an unknown mechanism of how cells ‘remember’ their identity when they divide – the cells’ so-called epigenetic memory. As time passes and we get older, many cells need to replenish themselves. They do so by dividing into new cells: Heart cells, skin cells and so on.

But when cells continue to divide and make new cells, they lose some of the information from their mother cell...

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Chiral Phonons Create Spin Current Without needing Magnetic Materials

 Spin Seebeck effect, chiral-phonon-activated spin Seebeck effect (CPASS) and experimental setup

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill used chiral phonons to convert wasted heat into spin information – without needing magnetic materials. The finding could lead to new classes of less expensive, energy-efficient spintronic devices for use in applications ranging from computational memory to powergrids.

Spintronic devices are electronic devices that harness the spin of an electron, rather than its charge, to create current used for data storage, communication, and computing...

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Small Planets Orbiting Low-Mass Stars detected with the SPIRou instrument and the TESS satellite

Small planets orbiting low-mass stars detected with the SPIRou instrument and the TESS satellite
The SPIRou instrument during its integration into the Canada-France-Hawaii Telescope. Credit: S. Chastanet, OMP/IRAP/CNRS

Since the discovery in 1995 of a planet in orbit around a star other than the sun, research in exoplanetology has revolutionized our knowledge of planetary systems. The SPIRou instrument, installed at the Canada-France-Hawaii Telescope, contributes to these results, in particular by observing the possible planets identified by the TESS observatory satellite.

By combining the data from both instruments, the planet TOI-1695b has been discovered, and is one of the new sub-Neptune and super-Earth type planets revealed by SPIRou around stars less massive and cooler than the sun, by an international team in which the Institut d’astrophysique de Paris plays a major role...

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Fructose could drive Alzheimer’s disease

An evolutionary human foraging instinct, fueled by fructose production in the brain, may hold clues to the development and possible treatment of Alzheimer’s disease (AD), according to researchers at the University of Colorado Anschutz Medical Campus.

The study, published recently in The American Journal of Clinical Nutrition, offers a new way of looking at a fatal disease characterized by abnormal accumulations of proteins in the brain that slowly erode memory and cognition.

“We make the case that Alzheimer’s disease is driven by diet,” said the study’s lead author Richard Johnson, MD, professor at the University of Colorado School of Medicine specializing in renal disease and hypertension...

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