The entirety of the known universe is teeming with an infinite number of molecules. But what fraction of these molecules have potential drug-like traits that can be used to develop life-saving drug treatments? Millions? Billions? Trillions? The answer: novemdecillion, or 10^60. This gargantuan number prolongs the drug development process for fast-spreading diseases like COVID-19 because it is far beyond what existing drug design models can compute. To put it into perspective, the Milky Way has about 100 thousand million, or 10^8, stars.

In a paper that will be presented at the International Conference on Machine Learning (ICML), MIT research...

A thermoelectric metal oxide film with a thermoelectric figure of merit of ~0.55 at 600°C has been discovered, opening new avenues towards the widespread use of thermoelectric converters.

Waste heat is a very promising source of energy conservation and reuse, by means of converting this heat into electricity — a process called thermoelectric conversion.

Commercially available thermoelectric conversion devices are synthesized using rare metals. While these are quite efficient, they are expensive and, in the majority of cases, utilize toxic materials...

The first ever exoplanets were discovered 30 years ago around a rapidly rotating star, called a pulsar. Now, astronomers have revealed that these planets may be incredibly rare. The new work will be presented tomorrow (Tuesday 12 July) at the National Astronomy Meeting (NAM 2022) by Iuliana Nițu, a PhD student at the University of Manchester.

The processes that cause planets to form, and survive, around pulsars are currently unknown...

Neutrophils promote irregularities while macrophages protect against them. Patients with heart disease are at risk of experiencing a potentially lethal “electrical storm” involving recurrent episodes of a type of irregular heartbeat called ventricular tachycardia (VT).

Electric shock therapy is used to treat VT following a heart attack, but unfortunately, options to prevent its recurrence are limited.

New research led by investigators at Massachusetts General Hospital (MGH) reveals that two different white blood cell types influence VT in the heart, suggesting that treatments that influence these cells may help reduce patients’ risk of sudden cardiac death.

The work, which is pu...