Opioid use is highly effective for pain management but is associated with high rates of addiction and deaths due to overdose. Now, an international team of researchers has developed a soft, bioresorbable, implantable device which can provide a cooling effect to peripheral nerves, leading to blocking of pain signals. The device demonstrated high precision and efficacy in rat models with spared nerve injuries and can serve as an effective substitute for opioids.

Owing to their high efficacy, opioids are used widely for the management of neuropathic pain, despite the increasing rates of opioid addiction and deaths due to overdose. To avoid these side effects, there is an urgent need for pain management approaches that can substitute opioid use.

It is well known that cold temperatur...

Researchers at the U.S. Department of Energy’s (DOE’s) National Renewable Energy Laboratory (NREL) made a technological breakthrough and constructed a perovskite solar cell with the dual benefits of being both highly efficient and highly stable.

The work was done in collaboration with scientists from the University of Toledo, the University of Colorado-Boulder, and the University of California-San Diego.

A unique architectural structure enabled the researchers to record a certified stabilized efficiency of 24% under 1-sun illumination, making it the highest reported of its kind...

Jupiter-sized planets can be stolen or captured by massive stars in the densely populated stellar nurseries where most stars are born, a new study has found.

Researchers from the University of Sheffield have proposed a novel explanation for the recently discovered B-star Exoplanet Abundance STudy (BEAST) planets. These are Jupiter-like planets at large distances (hundreds of times the distance between the Earth and the Sun) from massive stars.

Until now their formation has been something of a mystery, as massive stars emit large amounts of ultraviolet radiation that stops planets from growing to the size of Jupiter – the largest planet in our solar system.

Dr Emma Daffern-Powell, Co-author of the study, from the University of Sheffield’s Department of Physicsand Astronomy add...

New findings from Flinders University have demonstrated a molecular link between COVID-19 and serotonin cells in the gut.

The research could help provide further clues to what could be driving COVID-19 infection and disease severity and supports previous evidence that antidepressants, known as selective serotonin reuptake inhibitors (SSRIs), could reduce the severity of COVID symptoms.

COVID-19 displays an array of symptoms, which can regularly include gastrointestinal issues such as diarrhoea. Recent research has indicated that these gut symptoms in COVID-19 patients worsen with the severity of the disease, and this is linked to heightened gut-derived serotonin, released to cause gut dysfunction, increasing the body’s immune response and potentially worsening patient outcomes.