New Research Model illuminates How Organs Communicate with each other

A novel mouse model for mapping protein communication between organs. Proteins are labeled by biotin and their movement in the body can be tracked. Credit: Scripps Research and University of Southern California

Researchers uncover the proteins involved in key communication networks, which could help us better understand conditions like cancer and obesity. Our many different organ systems are in constant communication with each other. During exercise, for example, muscles send out signals to fat and liver tissue to release their energy sources. While these communication networks play a critical role in our bodies every day, it has been historically difficult to uncover such pathways...

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The new moisture-driven electricity generation device invented by NUS researchers capitalises on the difference in moisture content of the wet and dry regions of the carbon-coated fabric to create an electric current. Sea salt is used as a moisture absorbent for the wet region.

Researchers have developed a new moisture-driven electricity generation device made of a thin layer of fabric, sea salt, carbon ink, and a special water-absorbing gel. The device works by keeping one end of the fabric dry, while the other end is perpetually wet. The difference in moisture content of the wet and dry regions of the carbon-coated fabric creates an electric current...

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One of the Brightest Stars in the Sky is Evolving and Dying Before our Eyes

Four panels of artistic drawing of Betelgeuse. First panel, a small burst on the surface of the star is seen. On the 2nd, the material has begun to leave the star, the 3rd shows the material dark as it cools, and the 4th is the star back to normal
Artist’s impression of the aftermath of the SME, with the mass cooling and forming a cloud of dust which dimmed the star for a short period of time. The plot below outlines the real and expected brightness changes of Betelgeuse during this time. Credits: NASA, ESA, Elizabeth Wheatley (STScI)

Nothing lasts forever, including the stars in our night sky. One of the brighter and more notable stars in our sky is Betelgeuse, the bright red supergiant in the shoulder of Orion.

In late 2019, astronomers around the world grew giddy with excitement, because we saw this giant star get fainter than we’ve ever seen it before. Since Betelgeuse is at the end stages of its life, there was some speculation this might be a death rattle before the end.

But the cause of the “great dimming” wasn’t ...

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Scientists Uncover a New Role for Blood-Brain Barrier in Neuron Function and Damage

Findings open up a potential new avenue for therapies aimed at countering neurodegeneration. Researchers have made a surprising discovery linking Delta/Notch signaling in subperineurial glia (SPG) to the regulation of nerve ensheathment and neurotransmitter release at the Drosophila neuromuscular junction (NMJ). SPG, the counterpart of the endothelial layer in the vertebrate blood-brain barrier, form the key cellular layer that is critical for axonal ensheathment and the blood-brain barrier in Drosophila. The results provide a mechanistic insight into the biology of barrier function and glia-neuron interactions.

While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very littl...

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