Researchers identify Key Regulator of Blood Stem Cell Development

Illustration of red and white blood cells. Credit: Shutterstock

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at Weill Cornell Medicine.

The protein, known as histone H3.3, organizes the spool-like structures around which DNA is wrapped in plants, animals and most other organisms. Histones enable DNA to be tightly compacted, and serve as platforms for small chemical modifications – known as epigenetic modifications – that can loosen or tighten the wrapped DNA to control local gene activity.

The study, which appeared Dec. 27 in Nature Cell Biology, examined H3...

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New Power Transfer Technology provides unprecedented Freedom for Wireless Charging

Wireless charging of a retail robot at a test site. Photo: Prasad Jayathurathnage / Aalto University

Devices can be charged regardless of their position or orientation and even on the go. A new power transfer technology makes it possible to conveniently charge devices without using any wires or plugs. Warehouse robots, kitchen appliances, and even phones or laptops can receive power anywhere over the charging area, and because the power transfer continues even while the device is in motion, this technology could one day power electric vehicles while they’re on the go.

The basics of wireless power transfer have been in place for some time, but existing systems are not able to charge devices placed anywhere within a large area...

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Hubble Spots a Starship-Shaped Galactic Pair

The subject of this image is a group of three galaxies, collectively known as NGC 7764A. They were imaged by the NASA/ESA Hubble Space Telescope, using both its Advanced Camera for Surveys and Wide Field Camera 3. The two galaxies in the upper right of the image appear to be interacting with one another. The long trails of stars and gas extending from them give the impression that they have both just been struck at great speed, thrown into disarray by the bowling-ball-shaped galaxy to the lower left of the image.

In reality, interactions between galaxies happen over very long time periods, and galaxies rarely collide head-on with one another...

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Activated Protein C can Protect Against Age-related Cardiac Ischemia and Reperfusion Injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients’ tolerance to reperfusion injury — a potentially adverse effect of treatment for ischemic heart disease.

The research, published online Dec. 21 in Circulation Research, suggests that drugs derived from APC may limit ischemia and reperfusion-induced heart damage (reperfusion injury for short) and thereby help preserve cardiac function in older hearts.

Advanced age is a major risk factor for ischemic heart disease, often caused by a buildup of plaques in coronary arteries that narrows the vessels and restricts the supply of oxygenated blood to the heart. This “hardening of the arteries” can eventually trigger a heart attack.

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