Researchers have discovered that gene variants associated with risk of developing Alzheimer’s disease disturb the brain’s natural protective mechanism against the condition.

The brain has a natural protective mechanism against Alzheimer’s disease, and researchers at Baylor College of Medicine, Texas Children’s Hospital and collaborating institutions have discovered that gene variants associated with risk of developing the disease disturb the protective mechanism in ways that can lead to neurodegeneration. The researchers also showed in a fruit fly model of the condition that a chemical known as ABCA1 agonist can restore certain alterations of the brain protective mechanism.

The team reveals evidence supporting reactive oxygen species (ROS), natural byproducts of cellular metabol...

The field of self-repairing materials is rapidly expanding, and what used to be science fiction might soon become reality, thanks to scientists who developed eco-friendly nanocrystal semiconductors capable of self-healing. Their findings describe the process, in which a group of materials called double perovskites display self-healing properties after being damaged by the radiation of an electron beam.

From the Terminator to Spiderman’s suit, self-repairing robots and devices abound in sci-fi movies. In reality, though, wear and tear reduce the effectiveness of electronic devices until they need to be replaced...

Why the sun’s corona reaches temperatures of several million degrees Celsius is one of the great mysteries of solar physics. A “hot” trail to explain this effect leads to a region of the solar atmosphere just below the corona, where sound waves and certain plasma waves travel at the same speed...

Researchers have solved a decade-long mystery about a critical protein linked to Parkinson’s disease that could help to fast-track treatments for the incurable disease.

The research, published in Nature, has for the first time produced a ‘live action’ view of the protein, called PINK1, in exquisite molecular detail. The discovery explains how the protein is activated in the cell, where it is responsible for initiating the removal and replacement of damaged mitochondria...