Memory Killer T cells are primed in the Spleen during Influenza infection

Illustration of a T lymphocyte, or T cell, white blood cells targeting SARS-CoV-2 coronavirus particles. T lymphocytes are components of the body's immune system. Helper T cells stimulate other immune cells to act against a pathogen, whereas killer T cells target and destroy infected cells themselves. SARS-CoV-2 emerged in Wuhan, China, in December 2019, and causes a mild respiratory illness (covid-19) that can develop into pneumonia and be fatal in some cases.
This finding upends the long-held paradigm that priming during lung infections takes place only in the draining lymph nodes, and it will be key to developing more efficient vaccinations and therapies for respiratory challenges.

CD8+ T cells – known as “killer” T cells – are the assassins of the immune system. Once they are primed, they seek out and destroy other cells that are infected with virus or cells that are cancerous.

Priming involves dendritic cells – sentinels of the immune system. In an influenza infection in the lungs, for example, lung-migratory dendritic cells capture a piece of the viral antigen, and then migrate out of the lung to the place where naïve T cells reside, to present that antigen to the CD8+ T cells. This primes the T cells to know which cells to attack.

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A Universal System for Decoding any Type of Data sent across a Network

chip using novel GRAND algorithm graphic
Caption: A new silicon chip can decode any error-correcting code through the use of a novel algorithm known as Guessing Random Additive Noise Decoding (GRAND).
Credits:Image: Jose-Luis Olivares, MIT, with chip courtesy of the researchers

New chip eliminates the need for specific decoding hardware, could boost efficiency of gaming systems, 5G networks, IoT, and more. Every piece of data that travels over the internet — from paragraphs in an email to 3D graphics in a virtual reality environment — can be altered by the noise it encounters along the way, such as electromagnetic interference from a microwave or Bluetooth device. The data are coded so that when they arrive at their destination, a decoding algorithm can undo the negative effects of that noise and retrieve the original data...

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Affordable Housing in Outer Space: Scientists Develop Cosmic Concrete from Space Dust and Astronaut Blood

Transporting a single brick to Mars can cost more than a million British pounds – making the future construction of a Martian colony seem prohibitively expensive. Scientists at The University of Manchester have now developed a way to potentially overcome this problem, by creating a concrete-like material made of extra-terrestrial dust along with the blood, sweat and tears of astronauts.

In their study, published today in Materials Today Bio, a protein from human blood, combined with a compound from urine, sweat or tears, could glue together simulated moon or Mars soil to produce a material stronger than ordinary concrete, perfectly suited for construction work in extra-terrestrial environments.

The cost of transporting a single brick to Mars has been estimated at about US$2 mill...

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Study links Severe COVID-19 to Increase in Self-Attacking Antibodies

An illustration of antibodies among blood cells.
SciePro/Shutterstock.com

Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies than people without COVID-19, according to a new study. Autoantibodies can be early harbingers of full-blown autoimmune disease. “If you get sick enough from COVID-19 to end up in the hospital, you may not be out of the woods even after you recover,” said PJ Utz, MD, professor of immunology and rheumatology at Stanford Medicine.

Utz shares senior authorship of the study, which will be published Sept...

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