exercise tagged posts

Mimicking the benefits of exercise with a single molecule

Mimicking the benefits of exercise with a single molecule

Capital Medical University, in collaboration with the Chinese Academy of Sciences, reports that betaine, a molecule produced in the kidney and enhanced through sustained exercise, operates as a potent inhibitor of inflammatory and aging-related pathways.

Regular physical activity boosts health across cardiovascular, metabolic, and neurological systems. Scientists have traced improvements in immune function, insulin sensitivity, clearing of senescent cells and tissue regeneration to consistent physical activity. Earlier animal studies suggested that long-term exercise can delay aging processes and reduce vulnerability to chronic disease.

Precise molecular explanations for how sustained exercise reshapes human biology remain incomplete...

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When Muscles Work Out, they Help Neurons to Grow

Two textured green balls have a purple center.
Caption:In response to biochemical and physical cues of exercise, motor neurons (in purple) exhibit new growth (in green) faster than neurons that experience no exercise-induced cues.
Credits:Credit: Angel Bu

The findings suggest that biochemical and physical effects of exercise could help heal nerves. There’s no doubt that exercise does a body good. Regular activity not only strengthens muscles but can bolster our bones, blood vessels, and immune system.

Now, MIT engineers have found that exercise can also have benefits at the level of individual neurons. They observed that when muscles contract during exercise, they release a soup of biochemical signals called myokines...

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Some benefits of Exercise stem from the Immune System, suggests new study

Two images comparing inflammation in hindleg muscles of mice
The hind leg muscles of mice lacking Treg cells (right) showed prominent signs of inflammation after regular exercise, compared with those of mice with intact Tregs (left). The research showed that this uncontrolled inflammation negatively impacted muscle metabolism and function. Images: Kent Langston/Mathis Lab, HMS

The connection between exercise and inflammation has captivated the imagination of researchers ever since an early 20th-century study showed a spike of white cells in the blood of Boston marathon runners following the race.

Now, a new Harvard Medical School study published in Science Immunology may offer a molecular explanation behind this century-old observation.

The study, in mice, suggests that the beneficial effects of exercise may be driven, at least partly, by ...

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Exercise seems to Protect against Major Brain Hemorrhage

Photo: Getty Images

Regular physical activity and exercise may reduce bleeding in individuals with intracerebral hemorrhage, a University of Gothenburg study shows. The researchers emphasize the importance of physical activity to protect the brain.

The study, published in the journal Stroke and Vascular Neurology, analyzed data on 686 people treated for intracerebral hemorrhage at Sahlgrenska University Hospital in Gothenburg during the years 2014 to 2019.

The results are based on a retrospective analysis. Causal connections cannot be identified, but the findings are nonetheless clear: Those who reported regular physical activity had smaller hemorrhages than those who reported being inactive.

Physically active was defined as engaging in at least light physical activity, such a...

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