fibromyalgia tagged posts

Fibromyalgia likely the result of Autoimmune Problems

Passive transfer of fibromyalgia symptoms from patients to miceJournal of Clinical Investigation, 2021; 131 (13) DOI: 10.1172/JCI144201

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London, in collaboration with the University of Liverpool and the Karolinska Institute, has shown that many of the symptoms in fibromyalgia syndrome (FMS) are caused by antibodies that increase the activity of pain-sensing nerves throughout the body.

The results show that fibromyalgia is a disease of the immune system, rather than the currently held view that it originates in the brain.

The study, published today in the Journal of Clinical Investigation, demonstrates that the increased pain sensitivity, muscle weakness, reduced movement, and reduc...

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Gut Bacteria associated with Chronic Pain for first time

Human gut microbiome composition shows an enormous richness. Each circle represents a bacterial species, while the different colours mark different bacterial phyla. Credit: Dr. Amir Minerbi

People with fibromyalgia show variations in microbiome composition. A research team has shown, for the first time, that there are alterations in the bacteria in the gastrointestinal tracts of people with fibromyalgia. Approximately 20 different species of bacteria were found in either greater or are lesser quantities in the microbiomes of participants suffering from the disease than in the healthy control group.

Fibromyalgia affects 2-4 percent of the population and has no known cure...

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Does Insulin Resistance cause Fibromyalgia?


Effect of metformin treatment on pain as measured by the NPRS (0–10 scale).

A newly confirmed link with insulin resistance may radically change the way fibromyalgia and related forms of chronic pain are identified and managed. Researchers led by a team from The University of Texas Medical Branch at Galveston were able to dramatically reduce the pain of fibromyalgia patients with medication that targeted insulin resistance.

This discovery could dramatically alter the way that chronic pain can be identified and managed. Dr. Miguel Pappolla, UTMB professor of neurology, said that although the discovery is very preliminary, it may lead to a revolutionary shift on how fibromyalgia and related forms of chronic pain are treated...

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