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    longevity tagged posts

    Probiotic company finds Links between Youthful Gut Microbiota and Potential Centenarians

    April 13, 2023, Categories  Health/Medical, Biology/Biotechnology

    Probiotic company finds links between youthful gut microbiota and potential centenarians
    Comparisons of microbial compositions between baseline and follow-up. (a) aPCoA of the Bray‒Curtis distance plot for baseline and follow-up after adjusting for hypertension, medication use, and alcohol and tea drinking. (b) α-Diversity differences between baseline and follow-up for stratified health statuses (HB, n = 21; HF, n = 15; LHB, n = 19; LHF, n = 27). (c) Composition of the gut microbiome at the phylum level between baseline and follow-up for stratified health statuses. (d) LEfSe between baseline and follow-up stratified by health status (two-sided Kruskal‒Wallis test between classes; P < 0.05, LDA > 2). Healthy baseline (HB, n = 21), healthy follow-up (HF, n = 15), less healthy baseline (LHB, n = 19) and less healthy follow-up (LHF, n = 27) samples were examined...
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    Clusters of Genes help Mice Live Longer

    October 14, 2022, Categories  Health/Medical, Biology/Biotechnology

    Genetic analyses in UM-HET3 mice used in the Interventions Testing Program highlight sex- and
    age-specific longevity loci. Body weight associates with longevity, as does litter size, through its effect on
    body weight. Mendelian randomization in humans recapitulated these relationships between early growth
    and life span. Gene expression analyses, cross-species integration, and Caenorhabditis elegans life-span
    experiments highlight candidate longevity genes and provide a resource for further investigation.

    Researchers from the National Institute on Aging (NIA)-funded Interventions Testing Program recently reported the discovery of multiple candidate genes that influence longevity...

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    Secrets of Aging Revealed in Largest Study on Longevity, Aging in Reptiles and Amphibians

    June 24, 2022, Categories  Health/Medical, Biology/Biotechnology

    Painted turtle (stock image).
    Credit: © Brian E Kushner / stock.adobe.com

    An international team of 114 scientists reports the most comprehensive study of aging and longevity to date of reptiles and amphibians worldwide. Among their many findings, they document for the first time that turtles, crocodilians and salamanders have particularly low aging rates and extended lifespans for their sizes. The team also finds that protective phenotypes, such as the hard shells of most turtle species, contribute to slower aging, and in some cases even ‘negligible aging’ – or lack of biological aging.

    At 190 years old, Jonathan the Seychelles giant tortoise recently made news for being the “oldest living land animal in the world...

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    Cutting Calories and Eating at the Right Time of day leads to Longer Life in Mice

    May 7, 2022, Categories  Health/Medical, Biology/Biotechnology

    Experiments that tested various diet plans in mice found that the animals live longest on a low-calorie diet with daily fasting periods. Credit: Fernando Augusto/made-for.studio 

    In a study that followed hundreds of mice over their lifespans, calorie restriction combined with time-restricted eating boosted longevity. One recipe for longevity is simple, if not easy to follow: eat less. Studies in a variety of animals have shown that restricting calories can lead to a longer, healthier life.

    Now, new research suggests that the body’s daily rhythms play a big part in this longevity effect...

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