obesity tagged posts

Researchers have discovered an unexpected biological pathway by which brown fat cells can translate energy into heat. When we are exposed to sufficient cold or exercise, small clusters of brown fat cells in our bodies begin to burn up energy. Since 2009, when researchers at Joslin Diabetes Center and other institutions discovered that this helpful form of fat can be active in adults, scientists have sought to turn up the heat from these cells to treat obesity, diabetes and other metabolic conditions.

Researchers in the lab of Joslin’s Yu-Hua Tseng, PhD, a Senior Investigator in the Section on Integrative Physiology and Metabolism, now have dis...

A new study finds that the pleasure center of the brain and the brain’s biological clock are linked, and that high-calorie foods – which bring pleasure – disrupt normal feeding schedules, resulting in overconsumption.

During the years 1976 through 1980, 15% of U.S. adults were obese. Today, about 40% of adults are obese. Another 33% are overweight.

Coinciding with this increase in weight are ever-rising rates of heart disease, diabetes, cancer and health complications caused by obesity, such as hypertension...

Effects of hepatic Ago2-deficiency on MD-miRNA expression in the liver

New treatment for a major health problem? Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein in the livers of mice keeps the animals from getting fat and diabetic conditions.

Takahisa Nakamura, PhD, and colleagues at Cincinnati Children’s Hospital Medical Center genetically deleted a protein called Argonaute 2 (Ago2) from the livers of mice. Ago2 controls the silencing of RNA in cells, affecting energy metabolism in the body, according to the study...

Norbert Leitinger, Ph.D. (left), and Vlad Serbulea, Ph.D., of the University of Virginia School of Medicine, have determined why obesity causes harmful inflammation that can lead to diabetes, clogged arteries and other health problems. Doctors may be able to use this knowledge to battle these chronic diseases and others driven by damaging inflammation.
Credit: Dan Addison, University of Virginia Communications

Finding points to new approaches to battling diabetes, other chronic conditions. New research from the University of Virginia School of Medicine explains why obesity causes harmful inflammation that can lead to diabetes, clogged arteries and other health problems. Doctors may be able to use this knowledge to battle these chronic diseases and others driven by damaging inflammation...