EPFL researcher and last author Johan Auwerx is pictured. Credit: © EPFL / Alain Herzog
Intestinal bacteria transform a molecule contained in the fruit with spectacular results. As we age, our cells increasingly struggle to recycle mitochondria, thus accumulate in the cell. This degradation affects the health of many tissues, including muscles, which gradually weaken over the years. A buildup of dysfunctional mitochondria is also suspected of playing a role in other diseases of aging, such as Parkinson’s disease. The scientists identified a molecule that, all by itself, managed to re-establish the cell’s ability to recycle the components of the defective mitochondria: urolithin A...
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