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    Treatments for ALS tagged posts

    Pedal to the metal: Speeding up Treatments for ALS

    February 13, 2020, Categories  Health/Medical, Biology/Biotechnology

    TDP-43 is the red protein being expressed in yeast. Some of it is being sent to inside an organelle called the vacuole in yeast (lysosome in humans), which is the blue circle. Buchan describes the lysosome as the trash compactor/recycling depot of the cell that endocytosis and autophagy send their substrates too. (Courtesy: Ross Buchan)
    TDP-43 is the red protein being expressed in yeast. Some of it is being sent to inside an organelle called the vacuole in yeast (lysosome in humans), which is the blue circle. Buchan describes the lysosome as the trash compactor/recycling depot of the cell that endocytosis and autophagy send their substrates too. (Courtesy: Ross Buchan)

    A therapeutic intervention for amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig’s disease, could be on the horizon thanks to unexpected findings by University of Arizona researchers.

    ALS is the progressive degeneration of motor neurons that causes people to lose the ability to move and eventually speak, eat and breathe.

    Within the neuronal cells of patients with ALS and other neurodegenerative diseases, two proteins – TDP-43 and FUS – a...

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