Category Biology/Biotechnology

DNA Damage Repaired by Antioxidant Enzymes

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

Summary points

The human nucleus is metabolically active, according to the findings of a new study in Molecular Systems Biology by researchers at the CRG in Barcelona and CeMM/Medical University of Vienna,

In a state of crisis, such as widespread DNA damage, the nucleus protects itself by appropriates mitochondrial machinery to carry out urgent repairs that threaten the genome’s integrity

The findings represent a paradigm shift because the nucleus has been historically considered to be metabolically inert, importing all its needs through supply chains in the cytoplasm

Cancer hijacks cellular metabolism...

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Tiny Video Capsule shows promise as an Alternative to Endoscopy

Tiny Video Capsule Shows Promise as an Alternative to Endoscopy

While indigestible video capsule endoscopes have been around for many years, the capsules have been limited by the fact that they could not be controlled by physicians. They moved passively, driven only by gravity and the natural movement of the body. Now, according to a first-of-its-kind research study at George Washington University, physicians can remotely drive a miniature video capsule to all regions of the stomach to visualize and photograph potential problem areas. The new technology uses an external magnet and hand-held video game style joysticks to move the capsule in three-dimensions in the stomach. This new technology comes closer to the capabilities of a traditional tube-based endoscopy.

“A traditional endoscopy is an invasive procedure for patients, not to mention it i...

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A Conductive Self-Healing Hydrogel to Create Flexible Sensors

A conductive self-healing hydrogel to create flexible sensors
(a) Schematic diagram of self-healing mechanism of hydrogel; (b) self-healing rates 243 of hydrogel at different times; (c)Self-healing demonstration process of hydrogel; (d) 244 Self-healing effect of multiple healing with hydrogel. Credit: Wang et al.

Recent advancements in the field of electronics have enabled the creation of smaller and increasingly sophisticated devices, including wearable technologies, biosensors, medical implants, and soft robots. Most of these technologies are based on stretchy materials with electronic properties.

While material scientists have already introduced a wide range of flexible materials that could be used to create electronics, many of these materials are fragile and can be easily damaged...

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Eyedrops Slow Nearsightedness Progression in Kids

In addition to requiring life-long vision correction, nearsightedness, which starts in young kids, increases the risk for visual impairment later in life.
Photo: Getty Images

Clinical trial suggests low-dose atropine is effective myopia treatment. The results of a new clinical trial suggest that the first drug therapy to slow the progression of nearsightedness in kids could be on the horizon.

The three-year study found that a daily drop in each eye of a low dose of atropine, a drug used to dilate pupils, was better than a placebo at limiting eyeglass prescription changes and inhibiting elongation of the eye in nearsighted children aged 6 to 10.

That elongation leads to myopia, or nearsightedness, which starts in young kids and continues to get worse into the teen years before leve...

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