Category Health/Medical

Researchers leverage AI to Develop Early Diagnostic Test for Ovarian Cancer

Micrograph of a mucinous ovarian tumor (Photo National Institutes of Health)
Micrograph of a mucinous ovarian tumor (Photo National Institutes of Health)

For over three decades, a highly accurate early diagnostic test for ovarian cancer has eluded physicians. Now, scientists in the Georgia Tech Integrated Cancer Research Center (ICRC) have combined machine learning with information on blood metabolites to develop a new test able to detect ovarian cancer with 93 percent accuracy among samples from the team’s study group.

John McDonald, professor emeritus in the School of Biological Sciences, founding director of the ICRC, and the study’s corresponding author, explains that the new test’s accuracy is better in detecting ovarian cancer than existing tests for women clinically classified as normal, with a particular improvement in detecting early-stage ovarian d...

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Re-energizing Mitochondria to Treat Alzheimer’s Disease

Alzheimer’s nerve cells manifest a decrease in the connections between nerve cells, called synapses, shown here within the blue circles. Half the synapse is marked with a red fluorescent stain and the other half with a yellow stain. Credit: Scripps Research

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells. In Alzheimer’s disease, the ability to make energy is compromised, and the connections between nerve cells (called synapses) eventually come apart and wither, causing new memories to fade and fail.

A Scripps Research team, reporting in the journal Advanced Science, has now identified the energetic reactions in brain cells that malfunction and lead to neurodegeneration...

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How Obesity Dismantles our Mitochondria: Study reveals Key Mechanism behind Obesity-related Metabolic Dysfunction

mitochondria
These colored streaks are mitochondrial networks within fat cells. Researchers from UC San Diego discovered that a high-fat diet dismantles mitochondria, resulting in weight gain. Photo credit: UC San Diego Health Sciences

The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities.

Now, researchers from University of California San Diego School of Medicine have shed new light on how obesity affects our mitochondria, the all-important energy-producing structures of our cells.

In a study published in Nature Metabolism, the researcher...

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Playing an Instrument linked to better Brain Health in Older Adults

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Playing an instrument linked to better brain health in older adults

Engaging in music throughout your life is associated with better brain health in older age, according to a new study published by experts at the University of Exeter.

Scientists working on PROTECT, an online study open to people aged 40 and over, reviewed data from more than a thousand adults over the age of 40 to see the effect of playing a musical instrument—or singing in a choir—on brain health. Over 25,000 people have signed up for the PROTECT study, which has been running for 10 years.

The team reviewed participants’ musical experience and lifetime exposure to music, alongside results of cognitive testing, to determine whether musicality helps to keep the brain sharp in later life.

The paper, “The...

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