
Cell atlas of human thymus could help engineer improved therapeutic T cells. A first cell atlas of the human thymus gland could lead to new immune therapies to treat cancer and autoimmune diseases. Researchers from the Wellcome Sanger Institute, Newcastle University and Ghent University, Belgium, mapped thymus tissue through the human lifespan to understand how it develops and makes vital immune cells called T cells. In the future, this information could help researchers to generate an artificial thymus and engineer improved therapeutic T cells.
Published today (20 February) in Science, this human thymus atlas has revealed new cell types and identified signals that tell immature immune cells how to develop into T cells...
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