Self-assembling Nanofibers Prevent Damage from Inflammation

The graphic shows the peptide nanofiber bearing complement protein C3dg (blue) and key components of the TNF protein, which include B-cell epitopes (green), and T-cell epitopes (purple). Credit: Chelsea Fries
The graphic shows the peptide nanofiber bearing complement protein C3dg (blue) and key components of the TNF protein, which include B-cell epitopes (green), and T-cell epitopes (purple). Credit: Chelsea Fries

Nanomaterials strategically activate the immune system to fight inflammation as effectively as current standard therapeutics

Biomedical engineers at Duke University have developed a self-assembling nanomaterial that can help limit damage caused by inflammatory diseases by activating key cells in the immune system. In mouse models of psoriasis, the nanofiber-based drug has been shown to mitigate damaging inflammation as effectively as a gold-standard therapy.

One of the hallmarks of inflammatory diseases, like rheumatoid arthritis, Crohn’s disease and psoriasis, is the overpr...

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The Light-Bending Dance of Binary Black Holes

 Extreme gravity of two orbiting supermassive black holes distorts our view. In this visualization, disks of bright, hot, churning gas encircle both black holes, shown in red and blue to better track the light source. The red disk orbits the larger black hole, which weighs 200 million times the mass of our Sun, while its smaller blue companion weighs half as much Credit: NASA’s Goddard Space Flight Center/Jeremy Schnittman and Brian P. Powell

A pair of orbiting black holes millions of times the Sun’s mass perform a hypnotic pas de deux in a new NASA visualization. The movie traces how the black holes distort and redirect light emanating from the maelstrom of hot gas — called an accretion disk — that surrounds each one.

Viewed from near the orbital plane, each accretion disk takes ...

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Dietary Cocoa improves Health of Obese Mice; likely has Implications for Humans

This study used a commercially available cocoa product at a “physiologically achievable dose” — meaning its equivalent could be duplicated by humans. For people it works out to about 10 tablespoons of cocoa powder a day.
 IMAGE: GETTYIMAGES FCAFOTODIGITAL

Supplementation of cocoa powder in the diet of high-fat-fed mice with liver disease markedly reduced the severity of their condition, according to a new study by Penn State researchers, who suggest the results have implications for people.

Cocoa powder, a popular food ingredient most commonly used in the production of chocolate, is rich in fiber, iron and phytochemicals reported to have positive health benefits, including antioxidant polyphenols and methylxanthines, noted study leader Joshua Lambert, professor of food science ...

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3D-Printed Material to Replace Ivory

On the right: The new material Digory, ivory on the left

A new material called ‘Digory’ has been developed, which can be processed in 3D printers and is extremely similar to ivory. It can be used to restore old ivory artefacts. For centuries, ivory was often used to make art objects. But to protect elephant populations, the ivory trade was banned internationally in 1989. To restore ivory parts of old art objects, one must therefore resort to substitute materials — such as bones, shells or plastic. However, there has not been a really satisfactory solution so far.

TU Wien (Vienna) and the 3D printing company Cubicure GmbH, created as a spin-off of TU Wien, have now developed a high-tech substitute in cooperation with the Archdiocese of Vienna’s Department for the Care of Art and Monu...

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