Plasma cells at the center of a novel treatment approach. Researchers from Charité — Universitätsmedizin Berlin and the Deutsches Rheuma-Forschungszentrum (DRFZ) Berlin, a Leibniz Institute, have successfully treated two patients with the autoimmune disease systemic lupus erythematosus. Using daratumumab, a monoclonal antibody which targets specific immune cells known as plasma cells, the researchers were able to modulate the abnormal immunological memory processes found in these patients. Treatment induced sustainable clinical responses and resulted in a reduction in systemic inflammation. The results of this research have been published in the New England Journal of Medicine.

The body’s immunological memory enables the immune system to respond more rapidly and effectively to pa...

Scientists have come a step closer to the vision of a broad application of flexible, printable electronics. The team has succeeded in developing powerful vertical organic transistors with two independent control electrodes.

High-definition roll-up televisions or foldable smartphones may soon no longer be unaffordable luxury goods that can be admired at international electronics trade fairs...

An international team of astronomers, including a group from the University of Warwick, have discovered the first Ultra Hot Neptune planet orbiting the nearby star LTT 9779.

The world orbits so close to its star that its year lasts only 19 hours, meaning the stellar radiation heats the planet to over 1700 degrees Celsius.

At these temperatures, heavy elements like iron can be ionized in the atmosphere and molecules disassociated, providing a unique laboratory to study the chemistry of planets outside the solar system.

Although the world weighs twice as much as Neptune does, it is also slightly larger and so has a similar density...

Two pain blocking peptides were found in the venom from the Venezuelan Pinkfoot Goliath tarantula. Molecules from the venom of one of the world’s largest spiders could help University of Queensland-led researchers tailor pain blockers for people with irritable bowel syndrome (IBS).

Researchers screened 28 spiders, with the venom of the Venezuelan Pinkfoot Goliath tarantula — which has a leg-span of up to 30 centimetres — showing the most promise.

The team led by Professor Richard Lewis from UQ’s Institute for Molecular Bioscience in collaboration with Flinders University’s Professor Stuart Brierley and the South Australian Health and Medical Research Institute hopes to find effective pain relief for chronic intestinal pain.

“All pains are complex but gut pain is particularly ...