Abdominal obesity and muscle loss increase the risk of death by 83% after age 50, study finds

Abdominal obesity and muscle loss increase the risk of death by 83% after age 50
Excess fat intensifies inflammatory processes that trigger metabolic changes, aggravating muscle loss. Credit: Léo Ramos Chaves/Pesquisa FAPESP

A study by researchers at the Federal University of São Carlos (UFSCar) in Brazil, in partnership with University College London (UCL) in the United Kingdom, concluded that the combination of abdominal fat and muscle loss increases the risk of death by 83%, compared to people without these conditions.

This combination is so dangerous that it identifies an even greater problem: sarcopenic obesity. This condition is characterized by loss of muscle mass while gaining fat throughout the body. It is a difficult condition to diagnose, and it is related to loss of autonomy and a worsening quality of life in older adults...

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The monster hiding in plain sight: JWST reveals cosmic shapeshifter in the early universe

The monster hiding in plain sight: JWST reveals cosmic shapeshifter in the early universe
Covering a tiny patch of sky spanning less than a tenth of the full moon, the famous “Hubble eXtreme Deep Field” image revealed thousands of galaxies, including objects from the universe infancy. The James Webb Space Telescope observed the same region over three years. U of A researchers zoomed in on the galaxy reported in this study (inset), captured when the universe was only 800 million years old. The team found that even at its young age, it already harbored a supermassive black hole, shrouded in dust. Credit: ESA/Webb, NASA & CSA, G. Östlin, P. G. Perez-Gonzalez, J. Melinder, the JADES Collaboration, M. Zamani (ESA/Webb)

In a glimpse of the early universe, astronomers have observed a galaxy as it appeared just 800 million years after the Big Bang—a cosmic Jekyll and Hyde that loo...

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Soft ‘cyborg’ cardiac patches could improve stem cell heart repair

Illustration of a human heart model with a thin wired implant attached, magnified in a circle to show a yellow mesh-like electrode

Heart muscle cells grown from patient stem cells—known as human induced pluripotent stem cell–derived cardiomyocytes, or hiPSC-CMs—are a promising way to repair hearts damaged by heart attacks and heart failure. But transplanted hiPSC-CMs often have trouble syncing to the rhythm of native heart cells, which can cause dangerous arrhythmias after transplantation.

Efforts to improve cell integration
For years, stem cell biologists and cardiac researchers have been looking for ways to improve how implanted hiPSC-CMs mature and integrate into the heart. The challenge is that once the hiPSC-CMs are implanted in vivo, it’s hard to monitor how they integrate.

Now, Harvard University researchers have developed the first platform capable of continuously monitoring how transplanted ce...

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Tiny optical modulator could enable giant future quantum computers

quantum chip_with_light_coupled jake freedman eichenfield
Optical chip developed in the study with laser light from an optical fiber array. (Credit: Jake Freedman)

Researchers have made a major advance in quantum computing with a new device that is nearly 100 times smaller than the diameter of a human hair.

Published in the journal Nature Communications, the breakthrough optical phase modulators could help unlock much larger quantum computers by enabling efficient control of lasers required to operate thousands or even millions of qubits—the basic units of quantum information.

Critically, the team of scientists have developed these devices using scalable manufacturing, avoiding complex, custom builds in favor of those used to make the same technology behind processors already found in computers, phones, vehicles, home appliances—virtu...

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